Objective: This case-based review aims to list all the cases previously published in the literature about COVID-19 related to uveitis and to add a new case.

Materials and Methods: We searched articles about COVID-19 and uveitis.

Case presentation: A 51-year-old male patient with no previous chronic diseases received a diagnosis of AS in 2012 due to low back pain and recurrent uveitis. After he received his first dosage of the COVID-19 vaccine (Oxford-Astra-Zeneca, Fiocruz, Rio de Janeiro, Brazil) on Jun 17th, 2021 he experienced a new uveitis crisis (after 17 days) on his right eye, diagnosed by the ophthalmologist, which was characterized by a mild picture of light pain eyes, red eyes, and light sensation of a foreign body in the eye.

Results: A total of 86 patients are described, with the majority affected being male (52/86) and with a mean time to onset of uveitis symptoms after vaccination of 9.95 days. Patients with a history of uveitis accounted for 45% of the cases, while 18% had other previous diseases. The rate of patients who received drug treatment was 80%, while 89% corresponded to the patients who had a complete recovery.

Conclusions: This study reviewed all cases and adds one more case for uveitis after COVID-19 vaccine.