Paget bone disease demonstrated on 18F-fluorocholine PET/CT: a case report

https://doi.org/10.4081/br.2020.44

Authors

  • Antonella Laria | lariantonella@yahoo.it Rheumatology Unit, Fornaroli Hospital, Magenta (MI), Italy. https://orcid.org/0000-0002-5375-0951
  • Alfredomaria Lurati Rheumatology Unit, Fornaroli Hospital, Magenta (MI), Italy. https://orcid.org/0000-0003-2784-9816
  • Katia Angela Re Rheumatology Unit, Fornaroli Hospital, Magenta (MI), Italy.
  • Mariagrazia Marrazza Rheumatology Unit, Fornaroli Hospital, Magenta (MI), Italy.
  • Daniela Mazzocchi Rheumatology Unit, Fornaroli Hospital, Magenta (MI), Italy.
  • Paola Maria Faggioli Internal Medicine Unit, Ospedale Civile, Legnano (MI), Italy.
  • Antonino Mazzone Internal Medicine Unit, Ospedale Civile, Legnano (MI), Italy.

Abstract

Paget disease (PD) is a chronic disorder resulting in enlarged and misshapen bones, caused by disorganized bone remodeling. This case involves a 64-year-old man with prostatic adenocarcinoma and PD of some skeletal areas with increased uptake shown on 18 F-fluoro-methyl-choline (FMC) positron emission tomography/ computed tomography (PET/CT) performed for cancer restaging. Besides this feature, Paget disease may mimic metastases on PET/CT using various radiotracers, including 18 F-FMC PET/CT. In particular, this case highlights the potential of multiparametric disease characterization on PET. Therefore, in suspected cases, in which differential diagnosis is difficult, histology can be a helpful tool for diagnostic purposes.

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References

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Published
2020-12-28
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Section
Case Reports
Keywords:
Paget bone disease, 18F-fluorocholine PET/CT.
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How to Cite
Laria, A., Lurati, A., Re, K. A., Marrazza, M., Mazzocchi, D., Faggioli, P. M., & Mazzone, A. (2020). Paget bone disease demonstrated on 18F-fluorocholine PET/CT: a case report. Beyond Rheumatology, 2(3), 89–92. https://doi.org/10.4081/br.2020.44

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